
A woman bearing a child is not a matter of course, but a small
wonder. Many factors must come together at the right time so that a new
life can come into existence. As an estimate, every 10th couple in their
middle age is not able to have children. Many of these affected couples
go through a nerve-wracking and uncertain time, in which the possible
methods of the modern reproductive medicine are considered to fulfill
their desire to have children .
The in-vitro fertilization is one of
those methods. Read the 8 most important facts about the prospects,
workflow and the risks of IVF treatment:
1. Strictly speaking, IVF is not artificial insemination and does not take place in a test tube.
Although the Latin meaning of the word in-vitro fertilization is
“insemination in glass”, the so-called culture dishes are used in place
of the test tubes. Moreover, no artificial injection of the sperm is
done, but instead the egg and the sperms are brought together, only
outside of the body. The insemination is, therefore, “natural”, but only
outside the body.
2. IVF is a method that can help women become pregnant, who have problems with their Fallopian tubes.
If the Fallopian tubes are not
working, the egg cell cannot reach the uterus and cannot get lodged in
the uterus. In the in-vitro fertilization, therefore, the mature egg
cells are extracted and are brought together with the male sperm in an
incubator. Thereafter, the fertilized egg cells are transferred to the
uterus. In this way, the blocked Fallopian tubes can be bypassed.
3. An IVF treatment includes one complete female cycle.
On the
first day of the menstrual bleeding, the maturity of the egg cell is
enhanced by giving an injection, this is known as hormonal stimulation.
On the ninth day of the cycle, the maturity of the follicles is checked
by means of ultrasound and blood test. On the basis of this result, the
time of ovulation is determined. The egg cells are taken 36 hours after
the initial injection. The sperms of the male now have 24 hours for
fertilizing the egg cells in the culture dish. Around the 17th day of
the cycle, the fertilized egg cells can be placed back in the uterus.
About ten days later, the much-awaited pregnancy test can be done with a
hopefully positive result.
4. The hormonal stimulation has advantages and disadvantages.
Normally, one egg cell becomes mature
in the body of a woman in each cycle. An injection of natural
messengers can increase the number of the egg cells and hence also the
probability of success of the treatment. Every egg cell does not develop
into an embryo. If several embryos are present, the most promising one
can be selected from these. Possible side-effects are an increase in the
cycle symptoms, like headache and mood fluctuations. Even serious
problems like over-stimulation of the ovaries cannot be ruled out. Asper
experience, if a women decides to undergo an IVF treatment without
hormonal stimulation, the number of treatment cycles required increases.
5. Multiple and tubal pregnancies are possible risks.
The risk of a multiple pregnancy
increases, if several embryos are transferred to the uterus. In case of
two embryos, the probability for a twin pregnancy is around 10%. The
decision of, how many embryos should be used, is up to the couple. In
exceptional cases, a tubal pregnancy can also be caused, if the embryos
do not get lodged in the uterus, but instead in the Fallopian tube. Both
of the cases could cause pregnancy complications.
6. The chances of success of each embryo transfer are around 30 – 40%.
A lot of factors influence the
success rate of an in-vitro fertilization, including the age of the
woman, the reason for infertility and the number of embryos transferred.
The entire process of treatment is very fragile and does not always
succeed. In this case, it can be repeated in the next cycle. The doctor
clarifies, whether an interval between the cycles individually makes
sense.
7. ICSI is an alternative, if the fertilization outside of the body does not succeed naturally.
In case of IVF, the sperms and the
eggs should meet each other by themselves. If the sperms are too slow,
too weak or too few, they can be injected directly in the egg cell in
the laboratory (ICSI = Intracytoplastic Sperm Injection). This process
can be successful, even when the egg membrane (amnion) is thick. During
the course of the treatment, there is no difference between IVF and ICSI
for the couple.
8. During the IVF treatment, one should avoid smoking and intake of caffeine and alcohol.
Drugs and poisonous pleasures of all
kinds can harm the embryo and cause miscarriages and infertility. Sexual
intercourse, on the other hand, can be done during an IVF cycle.
Studies have even indicated that this improves the quality of the
embryos.